On Monday, August 29, 2005, Hurricane Katrina struck the Gulf Coast. Outside of the affected areas of TX, LA, MS, and AL, GA received the largest number of these evacuees, approximately 125,000. By August 30, 2005, GA began receiving a total of approximately 1,300 NDMS patients from flights arriving at Dobbins Air Force Base. Within days, Georgia established 13 shelters for evacuees. Crowded shelters can increase the risk for communicable diseases. In addition, many evacuees left behind needed medications, thus increasing the risk for chronic disease exacerbations.

On October 24, 2005, Hurricane Wilma made landfall on the southwest coast of Florida as a category 3 storm. The storm moved toward the northeast and passed through Palm Beach and Broward Counties before entering the Atlantic Ocean. Hurricane force winds and rain caused extensive damage to electrical infrastructure and traffic lights, and temporarily displaced thousands of residents. Power outages in Broward County affected over 90% of its 1.8 million residents, with some outages lasting >2 weeks. Boil water notices were declared for much of the county.