Hurricane Harvey made landfall in Texas on August 25, 2017, resulting in 88 fatalities and more than $125 billion in damages to infrastructure. In Houston, flooding created a toxic mix of chemicals, sewage, biohazards, and 8 million cubic yards of garbage. The level of biohazard exposure, as well as injuries from trauma among persons residing in affected areas, was widespread and likely contributed to increases in emergency department (ED) visits in Houston and cities that received persons evacuating from the hurricane.