North Carolina Disease Event Tracking and Epidemiologic Collection Tool (NC DETECT) is the Web-based early event detection and timely public health surveillance system in the North Carolina Public Health Information Network. At the present time NC DETECT monitors five data sources: emergency departments, the statewide poison center, the statewide EMS data collection system, a regional wildlife center and laboratories from the NC State College of Veterinary Medicine for suspicious patterns. NC DETECT receives Carolinas Poison Control Center (CPC) data every 24 hours as of August, 2005.

The United States Environmental Protection Agency (U.S. EPA) has developed a prototype contamination warning system (CWS) for drinking water in response to Homeland Security Presidential Directive 9 (HSPD9). The goal of HSPD9 and the CWS is to expedite contamination containment and emergency response, thereby minimizing public health and economic impacts.

Though spatio-temporal patterns of influenza spread have often suggested that environmental factors, such as temperature, solar radiation and humidity play a key role, few studies have directly assessed their effect on the timing of annual epidemics. Finkelman et al observed a significant positive relationship between the latitudinal position of temperate countries and epidemic timing. It is hypothesized that during winter months, in temperate regions, decreased skin exposure to sunlight affects immune function by altering the production of certain immunomodulators (e.g.