Enteric fever (EF) is a grave systemic infection, which has been controlled quite effectively in developed countries, but continues to be a grave public health concern for India. Environmental drivers such as rainfall, temperature, relative humidity and El Niño-Southern Oscillations (ENSO) are known to influence the transmission of Salmonella typhi and paratyphi. India possesses the largest population burden of EF, yet very few studies have explored its climatic associations.

Objective: This study is an attempt to explore the relationship of EF incidence with climate variables and ENSO events in the seventh most populous city in India.