In 2016, the BioSense Platform for national syndromic surveillance made substantial enhancements including data processing changes, a national ESSENCE instance, and management tools to support diverse data sharing needs. On August 21, 2017, a total solar eclipse occurred over much of the United States. The event resulted in large gatherings over multiple days to areas in the Path of Totality (PoT). In the days leading up to the event, public health and emergency preparedness included syndromic surveillance in their monitoring plans.